Primum Non Nocere: An Impossible Task in Medicine?
Keywords:
Primum non nocere, Overdiagnosis, Deprescribing, Decision-makingAbstract
- Are clinicians growing overly cautious in the name of “avoiding harm”?
- Overdiagnosis is a modern medical phenomenon underlied by expanded disease definitions, uncritical adoption of
- population screening and fear of uncertainty and new technology.
- International coordination is needed to improve current diagnostic standards and to promote effective deprescribing.
- Sometimes, avoiding harm means avoiding action.
Downloads
References
1. Too much medicine [Internet]. BMJ. [cited 2023 Apr 27]. Available from: https://www.bmj.com/too-much-medicine
2. Järvinen TLN, Michaëlsson K, Jokihaara J, Collins GS, Perry TL, Mintzes B, et al. Overdiagnosis of bone fragility in the quest to prevent hip fracture [Internet]. BMJ. British Medical Journal Publishing Group; 2015 [cited 2023Apr27]. Available from: https://www.bmj.com/content/350/ bmj.h2088
3. Review deprescribing: A primary care perspective [Internet]. EJHP. [cited 2023 Apr 27]. Available from: https://ejhp.bmj.com/content/ ejhpharm/24/1/37.full.pdf
4. Luymes CH, Poortvliet RKE, van Geloven N, de Waal MWM, Drewes YM, Blom JW, et al. Deprescribing preventive cardiovascular medication in patients with predicted low cardiovascular disease risk in general practice - the ecstatic study: A cluster randomised non-inferiority trial [Internet]. BMC. U.S. National Library of Medicine; 2018 [cited 2023Apr28]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763574/
5. Marsh H. Do no harm: Tales of life, death and brain surgery. London, UK: Weidenfeld & Nicolson; 2014.
Downloads
Published
How to Cite
Issue
Section
Categories
License
Copyright (c) 2025 Michaela Moriarty

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain copyright and grant the journal the right of first publication with the work simultaneously licensed under a Creative Commons Attribution (CC-BY) 4.0 License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
Provided they are the owners of the copyright to their work, authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work (e.g., post it to an institutional repository, in a journal or publish it in a book), with an acknowledgement of its initial publication in this journal.