Sleeping Sickness and the Issue with its Animal Models
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1. Kennedy, P. G. E. (2004). Hu- man African trypanosomiasis of the CNS: current issues and challenges. Journal of Clinical Investigation, 113, 496-504
2. Kennedy, P. G. E. (2007).Animal models of human Af- rican trypanosomiasis - very useful or too far removed? Transactions of the Royal Society of Tropical Medicine and Hygiene, 101, 1061-1062
3. WHO, Fact sheet N°259, Oc- tober 2010
4. Koshiuka, K., Elstner, E., Wil- liamson, E., Said, J. W., Tada, Y. & Koeffler, H. P. (2000). Novel therapeutic approach: organic arsenical (melarso- prol) alone or with all-trans -retinoic acid markedly inhib- it growth of human breast and prostate cancer cells in vitro and in vivo. British Jour- nal of Cancer, 82(2), 452-458
5. Grassi-Zucconi, G.,Harris, J. A., Mohammed, A. H., Am- brosini, M. V., Kristensson, K. & Bentivoglio, M. (1995). Sleep fragmentation, and changes in locomotor activ- ity and body temperature in trypanosome-infected rats. Brain Research Bulletin, 37 (2), 123-129
6. Amrouni, D., Meiller, A., Gautier-Sauvigné, S., Piraud, M., Bouteille, B., Vincen- deau, P., Buguet, A., Cespug- lio, R. (2011). Cerebral Changes Occurring in Argi- nase and Dimethylarginine Dimethylaminohydrolase
(DDAH) in a Rat Model of Sleeping Sickness. Plosone, 6 (3), art. no. e16891
7. Mdachi, R. E., Thuita, J. K., Kagira, J. M., Ngotho, J. M., Murilla, G. A., Ndung’u, J. M., Tidwell, R. R., Hall, J. E.
& Brun, R. (2009). Efficacy of the Novel Diamidine Com- pound 2,5-Bis(4-Amidino- phenyl)- Furan-Bis-O-Meth- lylamidoxime (Pafuramidine, DB289) against Trypanosoma brucei rhodesiense Infection in Vervet Monkeys after Oral Administration. Antimicro- bial Agents and Chemothera- py, 53 (3), 953-957
8. Masocha, W., Robertson, B., Rottenberg, M.E., Mhlanga, J., Sorokin, L. & Kristensson, K., (2004). Cerebral vessel laminins and IFNgamma define Trypanosoma brucei brucei penetration of the blood-brain barrier. The Jour- nal of clinical investigation, 114, 689-694.
9. Antoine-Moussiaux, N., Mages, S. & Desmecht, D. (2008). Contributions of ex- perimental mouse models to the understanding of African trypanosomiasis. Trends in Parasitology, 24, (9), 411-418
10. Ngotho, M., Kagira, J. M., Jensen, H. E., Karanja, S.
M., Farah, I. O. & Hau, J. (2009). Immunospecific im- munoglobulins and IL-10 as markers for Trypanosoma brucei rhodesiense late stage disease in experimentally infected vervet monkeys. Tropical Medicine and In- ternational Health, 14 (7), 736- 747
11. Sternberg, J. M., Rodgers,
J., Bradley, B., MacLean, L., Murray, M. & Kennedy, P. G. E. (2005). Meningoencepha- litic African trypanosomiasis: Brain IL-10 and IL-6 are asso- ciated with protection from neuro-inflammatory pathol- ogy. Journal of Neuroimmu- nology, 167, 81-89
2. Kennedy, P. G. E. (2007).Animal models of human Af- rican trypanosomiasis - very useful or too far removed? Transactions of the Royal Society of Tropical Medicine and Hygiene, 101, 1061-1062
3. WHO, Fact sheet N°259, Oc- tober 2010
4. Koshiuka, K., Elstner, E., Wil- liamson, E., Said, J. W., Tada, Y. & Koeffler, H. P. (2000). Novel therapeutic approach: organic arsenical (melarso- prol) alone or with all-trans -retinoic acid markedly inhib- it growth of human breast and prostate cancer cells in vitro and in vivo. British Jour- nal of Cancer, 82(2), 452-458
5. Grassi-Zucconi, G.,Harris, J. A., Mohammed, A. H., Am- brosini, M. V., Kristensson, K. & Bentivoglio, M. (1995). Sleep fragmentation, and changes in locomotor activ- ity and body temperature in trypanosome-infected rats. Brain Research Bulletin, 37 (2), 123-129
6. Amrouni, D., Meiller, A., Gautier-Sauvigné, S., Piraud, M., Bouteille, B., Vincen- deau, P., Buguet, A., Cespug- lio, R. (2011). Cerebral Changes Occurring in Argi- nase and Dimethylarginine Dimethylaminohydrolase
(DDAH) in a Rat Model of Sleeping Sickness. Plosone, 6 (3), art. no. e16891
7. Mdachi, R. E., Thuita, J. K., Kagira, J. M., Ngotho, J. M., Murilla, G. A., Ndung’u, J. M., Tidwell, R. R., Hall, J. E.
& Brun, R. (2009). Efficacy of the Novel Diamidine Com- pound 2,5-Bis(4-Amidino- phenyl)- Furan-Bis-O-Meth- lylamidoxime (Pafuramidine, DB289) against Trypanosoma brucei rhodesiense Infection in Vervet Monkeys after Oral Administration. Antimicro- bial Agents and Chemothera- py, 53 (3), 953-957
8. Masocha, W., Robertson, B., Rottenberg, M.E., Mhlanga, J., Sorokin, L. & Kristensson, K., (2004). Cerebral vessel laminins and IFNgamma define Trypanosoma brucei brucei penetration of the blood-brain barrier. The Jour- nal of clinical investigation, 114, 689-694.
9. Antoine-Moussiaux, N., Mages, S. & Desmecht, D. (2008). Contributions of ex- perimental mouse models to the understanding of African trypanosomiasis. Trends in Parasitology, 24, (9), 411-418
10. Ngotho, M., Kagira, J. M., Jensen, H. E., Karanja, S.
M., Farah, I. O. & Hau, J. (2009). Immunospecific im- munoglobulins and IL-10 as markers for Trypanosoma brucei rhodesiense late stage disease in experimentally infected vervet monkeys. Tropical Medicine and In- ternational Health, 14 (7), 736- 747
11. Sternberg, J. M., Rodgers,
J., Bradley, B., MacLean, L., Murray, M. & Kennedy, P. G. E. (2005). Meningoencepha- litic African trypanosomiasis: Brain IL-10 and IL-6 are asso- ciated with protection from neuro-inflammatory pathol- ogy. Journal of Neuroimmu- nology, 167, 81-89
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2012-01-01
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Rudolf, A. (2012). Sleeping Sickness and the Issue with its Animal Models. Trinity Student Medical Journal , 13(1), Page 46–48. Retrieved from https://ojs.tchpc.tcd.ie/index.php/tsmj/article/view/1819
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